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Opentargets Database

88TrustedShips scripts

Genetic and clinical data retrieval for drug discovery and disease association analysis.

What it does

Opentargets Database integrates multi-modal biological evidence to bridge the gap between genomic research and pharmaceutical development. By installing this skill, your assistant gains the ability to query diverse datasets, ranging from GWAS findings and QTL studies to clinical trial statuses and drug druggability metrics.

It functions as an interface for the Open Targets GraphQL API, handling the complexities of large-scale data retrieval, pagination, and retry logic. This allows users to programmatically extract evidence-based connections between genes and human diseases without manual lookup procedures.

When it earns its place

Reach for it when…

This skill is suited for translational research workflows where you need to identify promising therapeutic targets, assess gene druggability, or connect genetic variants to specific disease phenotypes through validated evidence.

Look elsewhere when…

It is not designed for browsing real-time medical literature or patient records, nor does it perform statistical analysis of raw sequencing data. If your goal is to analyze your own custom VCF files or perform local pathway enrichment calculations, a dedicated bioinformatics pipeline will be more appropriate.

What to say to use it

You never invoke a skill directly — the assistant picks it up when your request matches what it covers. These are the kinds of things that do that.

  • show me drugs currently in clinical trials for Crohn's disease
  • find the most likely causal genes for this variant
  • list all diseases associated with this Ensembl gene ID
  • what is the druggability status of this specific target gene
  • retrieve GWAS studies linked to rheumatoid arthritis

Install it

Install for all your projects

Copy the skill directory into your personal skills folder. Claude picks it up on its own the next time your request matches what it does — there is nothing to enable.

bash
git clone --depth 1 --branch main https://github.com/google-deepmind/science-skills.git /tmp/science-skills
mkdir -p ~/.claude/skills
cp -r /tmp/science-skills/skills/opentargets_database ~/.claude/skills/opentargets-database

Install for one project only

Put it in the project's own skills folder instead, so it can be committed and shared with everyone working on that repository.

bash
cp -r /tmp/science-skills/skills/opentargets_database .claude/skills/opentargets-database

If a skill of the same name exists in both places, the personal one wins.

Installing on Claude.ai or through the API instead? The full guide covers every surface.

Pair it with an MCP server

Opentargets Database changes how the work is done. These servers change what Claude can reach while doing it.

How skills and MCP servers differ →